Publications

Krolak T, Chan KY, Kaplan L, Huang Q, Wu J, Zheng Q, Kozareva V, Beddow T, Tobey IG, Pacouret S, Chen AT, Chan AY, Ryvkin D, Gu C, Deveman BE. A high-efficiency AAV for endothelial cell transduction throughout the central nervous system Nature Cardiovascular Research 2022. DOI: 10.1038/s44161-022-00046-4

Chen AT, Altschuler K, Zhan SH, Chan YA, Deverman BE. COVID-19 CG enables SARS-CoV-2 mutation and lineage tracking by locations and dates of interest. eLife 2021. DOI: 10.7554/eLife.63409

Luoni M, Giannelli S, Indrigo MT, Niro A, Massimino L, Iannielli A, Passeri L, Russo F, Morabito G, Calamita P, Gregori S, Deverman BE, Broccoli V. Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome Frontiers in Neuroanatomy 2020. DOI: 10.7554/eLife.52629

Haery L, Deverman BE, Matho KS, Cetin A, Woodard K, Cepko C, Guerin KI, Rego MA, Ersing I, Bachle SM, Kamens J, Fan M. Adeno-Associated Virus Technologies and Methods for Targeted Neuronal Manipulation Frontiers in Neuroanatomy 2019. DOI: 10.3389/fnana.2019.00093

Huang Q, Chan KY, Tobey IG, Chan AY, Poterba T, Boutros CL, Balazs AB, Daneman R, Bloom JM, Seed C, Deverman BE. Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. PLOS ONE 2019. DOI: 10.1371/journal.pone.0225206

Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K. Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies Nature Communications 2019. DOI: 10.1038/s41467-019-09770-1

Bedbrook CN, Deverman BE, Gradinaru V. Viral strategies for targeting the central and peripheral nervous systems. Annual Review of Neuroscience 2018. DOI: 10.1146/annurev-neuro-080317-062048.

Challis RC, Ravindra Kumar S, Chan KY, Challis C, Jang MJ, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration. Preprint on bioRxiv 2018. DOI: 10.1101/246405

Deverman BE, Ravina BM, Bankiewicz KS, Paul SM, Sah DWY Gene therapy for neurological disorders: progress and prospects Nature Reviews Drug Discovery 2018. DOI: 10.1038/nrd.2018.110

Zelikowsky, M., Hui, M., Karigo, T., Choe, A., Yang, B., Blanco, M.R., Beadle, K., Gradinaru, V., Deverman, B.E., and Anderson, D.J. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell, 2018. DOI: 10.1016/j.cell.2018.03.037.

Allen WE, Kauvar IV, Chen MZ, Richman EB, Yang SJ, Chan K, Gradinaru V, Deverman BE, Luo L, Deisseroth K. Global representations of goal-directed behavior in distinct cell types of mouse neocortex. Neuron 2017. DOI: 10.1016/j.neuron.2017.04.017

Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sanchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V. Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems. Nature Neuroscience 2017. DOI: 10.1038/nn.4593

Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature Biotechnology 2016. DOI: 10.1038/nbt.3440

Eid F, Chen AT, Chan KY, Huang Q, Zheng Q, Tobey IG, Pacouret S, Brauer PP, Keyes C, Powell M, Johnston J, Zhao B, Lage K, Tarantal AF, Chan YA, Deverman BE. Systematic multi-trait AAV capsid engineering for efficient gene delivery bioRxiv 2022. DOI: 10.1101/2022.12.22.521680

Huang Q, Chen AT, Chan KY, Sorensen H, Barry AJ, Azari B, Beddow T, Zheng Q, Zhao B, Tobey IG, Eid F, Chan YA, Deverman BE Targeting AAV vectors to the CNS via de novo engineered capsid-receptor interactions. bioRxiv 2022. DOI: 10.1101/2022.10.31.514553

Chen AT, Altschuler K, Zhan SH, Chan YA, Deverman BE. COVID-19 CG: Tracking SARS-CoV-2 mutations by locations and dates of interest. bioRxiv 2020. DOI: 10.1101/2020.09.23.310565v2

Zhan SH, Deverman BE, Chan AY. SARS-CoV-2 is well adapted for humans. What does this mean for re-emergence? bioRxiv, 2020. DOI: 10.1101/2020.05.01.073262.